Our biggest need is for adventures and supplementary material for GURPS Fourth Edition. These can relate to already-published Fourth Edition books, or they can stand alone. Note that it is hard to write supplementary material for Fourth Edition books that aren't out yet . . . so you probably shouldn't try.
Other things we definitely want to have LOTS of include:
GURPS Third Edition material. Lots of people are still playing 3e, after all. To the extent that material can be statted for both editions, good, but we WILL publish adventures that are 3e only, if they are otherwise good.
And, in particular, GURPS material for Transhuman Space
In Nomine. If it's double-statted for GURPS Third Edition, to match GURPS In Nomine, good.
Toon.
Generic (stat-free) roleplaying support material of every kind